Thyroid dysfunction in Down's syndrome.

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Thyroid dysfunction in Down syndrome.

BACKGROUND Down syndrome is associated with various forms of thyroid dysfunction, hypothyroidism being the most common. The additive effects of both co-morbid conditions lead to further amplification of the clinical problems in these children with Down syndrome. OBJECTIVE The purpose of this prospective study was to know the prevalence of thyroid dysfunction in Down Syndrome children below th...

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Thyroid dysfunction in Down's syndrome.

One hundred and sixteen children with Down's syndrome, living in the community, were examined for clinical or laboratory evidence of thyroid dysfunction. Three were hypothyroid and one was hyperthyroid. Twenty eight (29%) had thyroid autoantibodies. Autoimmune conditions were present in first or second degree relatives of 35 (30%) of the children, and in 17 (15%) this was a thyroid disorder. Th...

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Oxidative stress, thyroid dysfunction & Down syndrome

Down syndrome (DS) is one of the most common chromosomal disorders, occurring in one out of 700-1000 live births, and the most common cause of mental retardation. Thyroid dysfunction is the most typical endocrine abnormality in patients with DS. It is well known that thyroid dysfunction is highly prevalent in children and adults with DS and that both hypothyroidism and hyperthyroidism are more ...

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Anesthetic consideration in downs syndrome--a review.

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1985

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.60.12.1149